Expression of glypican 3 in placental site trophoblastic tumor

<p>Abstract</p> <p>Background</p> <p>Glypican-3 (GPC3) is a membrane-bound heparan sulfate proteoglycan that functions in embryonic cell growth and differentiation and is highly expressed in the placenta. GPC3 is mutated in Simpson-Golabi-Behmel syndrome, which is chara...

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Bibliographic Details
Main Authors: Yang Ximing J, Hui Pei, Ou-Yang Robin J, Zynger Debra L
Format: Article
Language:English
Published: BMC 2010-09-01
Series:Diagnostic Pathology
Online Access:http://www.diagnosticpathology.org/content/5/1/64