Dendrimers as Carriers for siRNA Delivery and Gene Silencing: A Review

RNA interference (RNAi) was first literaturally reported in 1998 and has become rapidly a promising tool for therapeutic applications in gene therapy. In a typical RNAi process, small interfering RNAs (siRNA) are used to specifically downregulate the expression of the targeted gene, known as the ter...

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Bibliographic Details
Main Authors: Jiangyu Wu, Weizhe Huang, Ziying He
Format: Article
Language:English
Published: Hindawi Limited 2013-01-01
Series:The Scientific World Journal
Online Access:http://dx.doi.org/10.1155/2013/630654