The direct and sustained consequences of severe placental hypoxia on vascular contractility.

INTRODUCTION:Preeclampsia is a major health problem in human pregnancy, severely complicating 5-8% of all pregnancies. The emerging molecular mechanism is that conditions like hypoxic stress trigger the release of placental messengers into the maternal circulation, which causes preeclampsia. Our obj...

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Bibliographic Details
Main Authors: Philippe Vangrieken, Salwan Al-Nasiry, Ger M J Janssen, Antje R Weseler, Marc E Spaanderman, Aalt Bast, Paul M H Schiffers
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC6108468?pdf=render