Role of the Mannose Receptor (CD206) in Innate Immunity to Ricin Toxin
The entry of ricin toxin into macrophages and certain other cell types in the spleen and liver results in toxin-induced inflammation, tissue damage and organ failure. It has been proposed that uptake of ricin into macrophages is facilitated by the mannose receptor (MR; CD206), a C-type lectin known...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2011-09-01
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Series: | Toxins |
Subjects: | |
Online Access: | http://www.mdpi.com/2072-6651/3/9/1131/ |