Role of the Mannose Receptor (CD206) in Innate Immunity to Ricin Toxin

The entry of ricin toxin into macrophages and certain other cell types in the spleen and liver results in toxin-induced inflammation, tissue damage and organ failure. It has been proposed that uptake of ricin into macrophages is facilitated by the mannose receptor (MR; CD206), a C-type lectin known...

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Bibliographic Details
Main Authors: Emily Gage, Maria O. Hernandez, Joanne M. O’Hara, Elizabeth A. McCarthy, Nicholas J. Mantis
Format: Article
Language:English
Published: MDPI AG 2011-09-01
Series:Toxins
Subjects:
Online Access:http://www.mdpi.com/2072-6651/3/9/1131/