A Pilot Study of Baseline Spatial Genomic Heterogeneity in Primary Gastric Cancers Using Multi-Region Endoscopic Sampling

A Pilot Study of Baseline Spatial Genomic Heterogeneity in Primary Gastric Cancers Using Multi-Region Endoscopic Sampling

Intertumoral heterogeneity among actionable biomarkers including ERBB2, FGFR2 and EGFR has been observed to occur under therapeutic pressure in advanced gastric cancer. However, baseline intratumoral heterogeneity at diagnosis is understudied and may impact clinical outcomes. We sought to explore in...

Full description

Bibliographic Details
Main Authors: Joseph Chao, Jeeyun Lee, Kyung Kim, So Young Kang, Taehyang Lee, Kyoung-Mee Kim, Seung Tae Kim, Samuel J. Klempner, Hyuk Lee
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-02-01
Series:Frontiers in Oncology
Subjects:
gastric cancer
intratumoral heterogeneity
endoscopy
precision medicine
circulating tumor DNA
Online Access:https://www.frontiersin.org/article/10.3389/fonc.2020.00225/full

Internet

https://www.frontiersin.org/article/10.3389/fonc.2020.00225/full

Similar Items