Inhibition of human carboxylesterases by ginsenosides: structure–activity relationships and inhibitory mechanism
Abstract Background Human carboxylesterases (hCES) are key serine hydrolases responsible for the hydrolysis of a wide range of endogenous and xenobiotic esters. Although it has been reported that some ginsenosides can modulate the activities of various enzymes, the inhibitory effects of ginsenosides...
Main Authors: | , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2019-12-01
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Series: | Chinese Medicine |
Subjects: | |
Online Access: | https://doi.org/10.1186/s13020-019-0279-0 |