In vivo reinsertion of excised episomes by the V(D)J recombinase: a potential threat to genomic stability.
It has long been thought that signal joints, the byproducts of V(D)J recombination, are not involved in the dynamics of the rearrangement process. Evidence has now started to accumulate that this is not the case, and that signal joints play unsuspected roles in events that might compromise genomic i...
| Main Authors: | , , , , , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2007-03-01
|
| Series: | PLoS Biology |
| Online Access: | http://europepmc.org/articles/PMC1820826?pdf=render |