Temporary CXCR3 and CCR5 Antagonism Following Vaccination Enhances Memory CD8 T Cell Immune Responses

Abstract Although current vaccination strategies have been successful at preventing a variety of human diseases, attempts at vaccinating against some pathogens such as AIDS and tuberculosis (TB) have been more problematic, largely because abnormally high numbers of antigen-specific CD8 + T cells are...

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Bibliographic Details
Main Authors: Rui Li, Nan Zhang, Miaomiao Tian, Zihan Ran, Mingjun Zhu, Haiyan Zhu, Fangting Han, Juan Yin, Jiang Zhong
Format: Article
Language:English
Published: BMC 2016-07-01
Series:Molecular Medicine
Online Access:http://link.springer.com/article/10.2119/molmed.2015.00218