Epigenetic control of Epstein Barr Virus transcription – relevance to viral life cycle?
DNA-methylation normally leads to silencing of gene expression but Epstein-Barr virus (EBV) provides an exception to the epigenetic paradigm. DNA-methylation is absolutely required for the expression of many viral genes. Although the viral genome is initially unmethylated in newly infected cells, it...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2013-08-01
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| Series: | Frontiers in Genetics |
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| Online Access: | http://journal.frontiersin.org/Journal/10.3389/fgene.2013.00161/full |