Endoplasmic reticulum stress and destruction of pancreatic β cells in type 1 diabetes

Abstract. Type 1 diabetes (T1D) results from dysfunction of pancreatic islets β cells. Recent studies supported that endoplasmic reticulum (ER) stress takes an important role in pancreatic β cell excessive loss, resulting in T1D. Here, we aimed to review the relationship between ER stress and T1D. A...

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Bibliographic Details
Main Authors: Zhao-Hui Cao, Zhuan Wu, Cong Hu, Min Zhang, Wu-Zhou Wang, Xiao-Bo Hu, Li-Shao Guo
Format: Article
Language:English
Published: Wolters Kluwer 2020-01-01
Series:Chinese Medical Journal
Online Access:http://journals.lww.com/10.1097/CM9.0000000000000583