Roles of Lysyl Oxidase Family Members in the Tumor Microenvironment and Progression of Liver Cancer

The lysyl oxidase (LOX) family members are secreted copper-dependent amine oxidases, comprised of five paralogues: LOX and LOX-like l-4 (LOXL1-4), which are characterized by catalytic activity contributing to the remodeling of the cross-linking of the structural extracellular matrix (ECM). ECM remod...

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Bibliographic Details
Main Authors: Hung-Yu Lin, Chia-Jung Li, Ya-Ling Yang, Ying-Hsien Huang, Ya-Tze Hsiau, Pei-Yi Chu
Format: Article
Language:English
Published: MDPI AG 2020-12-01
Series:International Journal of Molecular Sciences
Subjects:
Online Access:https://www.mdpi.com/1422-0067/21/24/9751