Nucleotide sequence analyses of the <it>MRP</it>1 gene in four populations suggest negative selection on its coding region

Nucleotide sequence analyses of the <it>MRP</it>1 gene in four populations suggest negative selection on its coding region

<p>Abstract</p> <p>Background</p> <p>The <it>MRP</it>1 gene encodes the 190 kDa multidrug resistance-associated protein 1 (MRP1/ABCC1) and effluxes diverse drugs and xenobiotics. Sequence variations within this gene might account for differences in drug resp...

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Bibliographic Details
Main Authors: Ryan Stephen, Ambrose Helen, Sew Pui-Hoon, Wang Zihua, Chong Samuel S, Lee Edmund JD, Lee Caroline GL
Format: Article
Language:English
Published: BMC 2006-05-01
Series:BMC Genomics
Online Access:http://www.biomedcentral.com/1471-2164/7/111

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http://www.biomedcentral.com/1471-2164/7/111

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