Data Mining of Atherosclerotic Plaque Transcriptomes Predicts STAT1-Dependent Inflammatory Signal Integration in Vascular Disease

Data Mining of Atherosclerotic Plaque Transcriptomes Predicts STAT1-Dependent Inflammatory Signal Integration in Vascular Disease

Atherosclerotic plaque development involves multiple extra- and intra-cellular signals engaging cells from the immune system and from the vasculature. Pro-inflammatory pathways activated by interferon gamma (IFNγ) and toll-like receptor 4 (TLR4) ligands are profoundly involved in plaque formation an...

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Bibliographic Details
Main Authors: Krzysztof Sikorski, Joanna Wesoly, Hans A. R. Bluyssen
Format: Article
Language:English
Published: MDPI AG 2014-08-01
Series:International Journal of Molecular Sciences
Subjects:
atherosclerosis
JAK-STAT signalling
IFNγ
TLR4
diagnostic markers
Online Access:http://www.mdpi.com/1422-0067/15/8/14313

Internet

http://www.mdpi.com/1422-0067/15/8/14313

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