Probabilistic reconstruction of the tumor progression process in gene regulatory networks in the presence of uncertainty

<p>Abstract</p> <p>Background</p> <p>Accumulation of gene mutations in cells is known to be responsible for tumor progression, driving it from benign states to malignant states. However, previous studies have shown that the detailed sequence of gene mutations, or the st...

Full description

Bibliographic Details
Main Authors: Dougherty Edward R, Yoon Byung-Jun, Esfahani Mohammad
Format: Article
Language:English
Published: BMC 2011-10-01
Series:BMC Bioinformatics