Loss of the PTH/PTHrP receptor along the osteoblast lineage limits the anabolic response to exercise.

Exercise and physical activity are critical to maintain bone mass and strength throughout life. Both exercise and physical activity subject bone to a unique combination of stimuli in the forms of dynamic loading and a systemic increase in parathyroid hormone (PTH). Although dynamic loading is consid...

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Bibliographic Details
Main Authors: Joseph D Gardinier, Conor Daly-Seiler, Niloufar Rostami, Siddharth Kundal, Chunbin Zhang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0211076