Influence of the fibroblastic reticular network on cell-cell interactions in lymphoid organs.

Secondary lymphoid organs (SLO), such as lymph nodes and the spleen, display a complex micro-architecture. In the T cell zone the micro-architecture is provided by a network of fibroblastic reticular cells (FRC) and their filaments. The FRC network is thought to enhance the interaction between immun...

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Bibliographic Details
Main Authors: Frederik Graw, Roland R Regoes
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS Computational Biology
Online Access:http://europepmc.org/articles/PMC3310707?pdf=render