Icariin affects cell cycle progression and proliferation of human retinal pigment epithelial cells via enhancing expression of H19

Background Aberrant proliferation of retinal pigment epithelial (RPE) cells under pathologic condition results in the occurrence of proliferative vitreoretinopathy (PVR). Icariin (ICA)-a flavonol glucoside-has been shown to inhibit proliferation of many cell types, but the effect on RPE cells is unk...

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Bibliographic Details
Main Authors: Yibing Zhang, Min Li, Xue Han
Format: Article
Language:English
Published: PeerJ Inc. 2020-03-01
Series:PeerJ
Subjects:
H19
Online Access:https://peerj.com/articles/8830.pdf