The Peripheral Inflammatory Response to Alpha-Synuclein and Endotoxin in Parkinson's Disease

The Peripheral Inflammatory Response to Alpha-Synuclein and Endotoxin in Parkinson's Disease

The immune system is activated in Parkinson's Disease (PD), as evidenced by neuroinflammatory changes within the brain as well as elevated immune markers in peripheral blood. Furthermore, inflammatory cytokine levels in the blood are associated with disease severity and rate of progression. How...

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Bibliographic Details
Main Authors: Alice J. White, Ruwani S. Wijeyekoon, Kirsten M. Scott, Nushan P. Gunawardana, Shaista Hayat, I. H. Solim, H. T. McMahon, Roger A. Barker, Caroline H. Williams-Gray
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-11-01
Series:Frontiers in Neurology
Subjects:
Parkinson's disease
immune system
alpha-synuclein
endotoxin
cytokines
Online Access:https://www.frontiersin.org/article/10.3389/fneur.2018.00946/full

Internet

https://www.frontiersin.org/article/10.3389/fneur.2018.00946/full

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