Non-redundant and redundant roles of cytomegalovirus gH/gL complexes in host organ entry and intra-tissue spread.

Herpesviruses form different gH/gL virion envelope glycoprotein complexes that serve as entry complexes for mediating viral cell-type tropism in vitro; their roles in vivo, however, remained speculative and can be addressed experimentally only in animal models. For murine cytomegalovirus two alterna...

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Bibliographic Details
Main Authors: Niels A W Lemmermann, Astrid Krmpotic, Jürgen Podlech, Ilija Brizic, Adrian Prager, Heiko Adler, Astrid Karbach, Yiquan Wu, Stipan Jonjic, Matthias J Reddehase, Barbara Adler
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-02-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.1004640