A novel blood-feeding detoxification pathway in Nippostrongylus brasiliensis L3 reveals a potential checkpoint for arresting hookworm development.

A novel blood-feeding detoxification pathway in Nippostrongylus brasiliensis L3 reveals a potential checkpoint for arresting hookworm development.

As part of on-going efforts to control hookworm infection, the "human hookworm vaccine initiative" has recognised blood feeding as a feasible therapeutic target for inducing immunity against hookworm infection. To this end, molecular approaches have been used to identify candidate targets,...

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Bibliographic Details
Main Authors: Tiffany Bouchery, Kara Filbey, Amy Shepherd, Jodie Chandler, Deepa Patel, Alfonso Schmidt, Mali Camberis, Adeline Peignier, Adam A T Smith, Karen Johnston, Gavin Painter, Mark Pearson, Paul Giacomin, Alex Loukas, Maria-Elena Bottazzi, Peter Hotez, Graham LeGros
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-03-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC5864084?pdf=render

Internet

http://europepmc.org/articles/PMC5864084?pdf=render

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