Does co-transplantation of mesenchymal and spermatogonial stem cells improve reproductive efficiency and safety in mice?

Does co-transplantation of mesenchymal and spermatogonial stem cells improve reproductive efficiency and safety in mice?

Abstract Background Spermatogonial stem cell transplantation (SSCT) is a promising therapy in restoring the fertility of childhood cancer survivors. However, the low efficiency of SSCT is a significant concern. SSCT could be improved by co-transplanting transforming growth factor beta 1 (TGFβ1)-indu...

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Bibliographic Details
Main Authors: Prashant Kadam, Elissavet Ntemou, Jaime Onofre, Dorien Van Saen, Ellen Goossens
Format: Article
Language:English
Published: BMC 2019-10-01
Series:Stem Cell Research & Therapy
Subjects:
Fertility restoration
Male infertility
Mesenchymal stem cells
Spermatogonial stem cells
Transplantation
Reproductive efficiency
Online Access:http://link.springer.com/article/10.1186/s13287-019-1420-9

Internet

http://link.springer.com/article/10.1186/s13287-019-1420-9

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