Reduced expression of miR-200 family members contributes to antiestrogen resistance in LY2 human breast cancer cells.

Reduced expression of miR-200 family members contributes to antiestrogen resistance in LY2 human breast cancer cells.

The role of miRNAs in acquired endocrine-resistant breast cancer is not fully understood. One hallmark of tumor progression is epithelial-to-mesenchymal transition (EMT), characterized by a loss of cell adhesion resulting from reduced E-cadherin and increased cell mobility. miR-200 family members re...

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Bibliographic Details
Main Authors: Tissa T Manavalan, Yun Teng, Lacey M Litchfield, Penn Muluhngwi, Numan Al-Rayyan, Carolyn M Klinge
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3633860?pdf=render

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http://europepmc.org/articles/PMC3633860?pdf=render

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