Polymyxin Delivery Systems: Recent Advances and Challenges

Polymyxin Delivery Systems: Recent Advances and Challenges

Polymyxins are vital antibiotics for the treatment of multiresistant Gram-negative ESKAPE pathogen infections. However, their clinical value is limited by their high nephrotoxicity and neurotoxicity, as well as their poor permeability and absorption in the gastrointestinal tract. This review focuses...

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Bibliographic Details
Main Authors:	Natallia V. Dubashynskaya, Yury A. Skorik
Format:	Article
Language:	English
Published:	MDPI AG 2020-04-01
Series:	Pharmaceuticals
Subjects:	polymyxin colistin drug delivery drug carriers antimicrobial resistance bioavailability
Online Access:	https://www.mdpi.com/1424-8247/13/5/83

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