Polymyxin Delivery Systems: Recent Advances and Challenges
Polymyxins are vital antibiotics for the treatment of multiresistant Gram-negative ESKAPE pathogen infections. However, their clinical value is limited by their high nephrotoxicity and neurotoxicity, as well as their poor permeability and absorption in the gastrointestinal tract. This review focuses...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2020-04-01
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Series: | Pharmaceuticals |
Subjects: | |
Online Access: | https://www.mdpi.com/1424-8247/13/5/83 |