Hippocampal CA2 Lewy pathology is associated with cholinergic degeneration in Parkinson’s disease with cognitive decline

Hippocampal CA2 Lewy pathology is associated with cholinergic degeneration in Parkinson’s disease with cognitive decline

Abstract Although the precise neuropathological substrates of cognitive decline in Parkinson’s disease (PD) remain elusive, it has long been regarded that pathology in the CA2 hippocampal subfield is characteristic of Lewy body dementias, including dementia in PD (PDD). Early non-human primate trace...

Full description

Bibliographic Details
Main Authors: Alan King Lun Liu, Tsz Wing Chau, Ernest Junwei Lim, Idil Ahmed, Raymond Chuen-Chung Chang, Michail E. Kalaitzakis, Manuel B. Graeber, Steve M. Gentleman, Ronald K. B. Pearce
Format: Article
Language:English
Published: BMC 2019-04-01
Series:Acta Neuropathologica Communications
Subjects:
Parkinson’s disease
Alzheimer’s disease
Cholinergic system
Diagonal band of Broca
CA2
Hippocampus
Online Access:http://link.springer.com/article/10.1186/s40478-019-0717-3

Internet

http://link.springer.com/article/10.1186/s40478-019-0717-3

Similar Items