TNF-α - mediated peripheral and central inflammation are associated with increased incidence of PND in acute postoperative pain

Abstract Background Acute postoperative pain plays an important role in the perioperative neurocognitive disorders (PND). The pathogenesis of PND is still unknown, but it is generally believed that peripheral and central nervous system inflammation play an important role, and acute postoperative pai...

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Bibliographic Details
Main Authors: Yu-fan Zhao, Hui-wen Yang, Ting-shun Yang, Wenxiu Xie, Zhong-hua Hu
Format: Article
Language:English
Published: BMC 2021-03-01
Series:BMC Anesthesiology
Subjects:
Online Access:https://doi.org/10.1186/s12871-021-01302-z