Galactose-Deficient IgA1 as a Candidate Urinary Polypeptide Marker of IgA Nephropathy?

In patients with IgA nephropathy (IgAN), circulatory IgA1 and IgA1 in mesangial deposits contain elevated amounts of galactose-deficient IgA1 (Gd-IgA1). We hypothesized that a fraction of Gd-IgA1 from the glomerular deposits and/or circulation may be excreted into the urine and thus represent a dise...

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Bibliographic Details
Main Authors: Hitoshi Suzuki, Landino Allegri, Yusuke Suzuki, Stacy Hall, Zina Moldoveanu, Robert J. Wyatt, Jan Novak, Bruce A. Julian
Format: Article
Language:English
Published: Hindawi Limited 2016-01-01
Series:Disease Markers
Online Access:http://dx.doi.org/10.1155/2016/7806438