Secondary Structural Model of MALAT1 Becomes Unstructured in Chronic Myeloid Leukemia and Undergoes Structural Rearrangement in Cervical Cancer

Long noncoding RNAs (lncRNAs) influence cellular function through binding events that often depend on the lncRNA secondary structure. One such lncRNA, metastasis-associated lung adenocarcinoma transcript 1 (MALAT1), is upregulated in many cancer types and has a myriad of protein- and miRNA-binding s...

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Bibliographic Details
Main Authors: Matthew C. Wang, Phillip J. McCown, Grace E. Schiefelbein, Jessica A. Brown
Format: Article
Language:English
Published: MDPI AG 2021-01-01
Series:Non-Coding RNA
Subjects:
Online Access:https://www.mdpi.com/2311-553X/7/1/6