RIPK3 Suppresses the Progression of Spontaneous Intestinal Tumorigenesis

RIPK3 Suppresses the Progression of Spontaneous Intestinal Tumorigenesis

Receptor-interacting protein 3 (RIPK3), a member of the family of serine/threonine protein kinases, emerged as a critical regulator of necroptosis. Downregulated expression of RIPK3 is correlated with poor prognosis in multiple tumor types. Here, we show that RIPK3 is involved in the progression of...

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Bibliographic Details
Main Authors: Qun Zhao, Jian Guo, Xinran Cheng, Yingying Liao, Yun Bi, Yingxia Gong, Xudong Zhang, Yang Guo, Xianhui Wang, Wei Yu, Shu Jin, Yan Tan, Xianjun Yu
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-04-01
Series:Frontiers in Oncology
Subjects:
RIPK3
intestinal tumorigenesis
APC mutant mouse model
STAT3 (signal transducer and activator of transcription 3)
IL-6 receptor antibody
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2021.664927/full

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https://www.frontiersin.org/articles/10.3389/fonc.2021.664927/full

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