Antigenic presentation of heterologous epitopes engineered into the outer surface-exposed helix 4 loop region of human papillomavirus L1 capsomeres

Antigenic presentation of heterologous epitopes engineered into the outer surface-exposed helix 4 loop region of human papillomavirus L1 capsomeres

<p>Abstract</p> <p>Background</p> <p>Human papillomavirus (HPV) L1 capsid proteins can self-assemble into pentamers (capsomeres) that are immunogenic and can elicit neutralizing antibodies. Structural modelling of L1 inter-pentameric interactions predicts that helix 4 (...

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Bibliographic Details
Main Authors: Murata Yoshihiko, Lightfoote Paula M, Rose Robert C, Walsh Edward E
Format: Article
Language:English
Published: BMC 2009-06-01
Series:Virology Journal
Online Access:http://www.virologyj.com/content/6/1/81

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http://www.virologyj.com/content/6/1/81

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