Four simple rules that are sufficient to generate the mammalian blastocyst.

Early mammalian development is both highly regulative and self-organizing. It involves the interplay of cell position, predetermined gene regulatory networks, and environmental interactions to generate the physical arrangement of the blastocyst with precise timing. However, this process occurs in th...

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Bibliographic Details
Main Authors: Silas Boye Nissen, Marta Perera, Javier Martin Gonzalez, Sophie M Morgani, Mogens H Jensen, Kim Sneppen, Joshua M Brickman, Ala Trusina
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-07-01
Series:PLoS Biology
Online Access:https://doi.org/10.1371/journal.pbio.2000737