Increase of ADAM10 level in coronary artery in-stent restenosis segments in diabetic minipigs: high ADAM10 expression promoting growth and migration in human vascular smooth muscle cells via Notch 1 and 3.

Increase of ADAM10 level in coronary artery in-stent restenosis segments in diabetic minipigs: high ADAM10 expression promoting growth and migration in human vascular smooth muscle cells via Notch 1 and 3.

This study aimed to identify major proteins in the pathogenesis of coronary artery in-stent restenosis (ISR) in diabetic minipigs with sirolimus-eluting stenting, and to investigate the roles of key candidate molecules, particularly ADAM10, in human arterial smooth muscle cells (HASMCs).The stents w...

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Bibliographic Details
Main Authors: Ke Yang, Lin Lu, Yan Liu, Qi Zhang, Li Jin Pu, Lin Jie Wang, Zhen Bing Zhu, Ya Nan Wang, Hua Meng, Xiao Jie Zhang, Run Du, Qiu Jing Chen, Wei Feng Shen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3873985?pdf=render

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http://europepmc.org/articles/PMC3873985?pdf=render

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