Inducing apoptosis of human colon cancer cells by an IGF-I D domain analogue peptide

<p>Abstract</p> <p>Background</p> <p>The resistance of tumour cells to apoptosis is a major contributor to the limited effectiveness of chemotherapies. Insulin-like growth factor I (IGF-I) has potential to protect cancer cells from variety of apoptotic challenges. This...

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Bibliographic Details
Main Authors: Seifalian Alexander M, Fuller Barry J, Sales Kevin M, Yang Shi Yu, Winslet Marc C
Format: Article
Language:English
Published: BMC 2008-02-01
Series:Molecular Cancer
Online Access:http://www.molecular-cancer.com/content/7/1/17