Current and future treatment options for exon 14 skipping alterations in non-small cell lung cancer

It has been over three decades since the hepatocyte growth factor (HGF) ligand and its receptor MET proto-oncogene (MET) pathway was established as promoting cancer growth and metastasis. MET exon 14 skipping ( METex14 ) alterations occur in 3–4% of all non-small cell lung cancer (NSCLC) patients, t...

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Bibliographic Details
Main Authors: Lingzhi Hong, Jianjun Zhang, John V. Heymach, Xiuning Le
Format: Article
Language:English
Published: SAGE Publishing 2021-02-01
Series:Therapeutic Advances in Medical Oncology
Online Access:https://doi.org/10.1177/1758835921992976