TP53 and PTEN mutations were shared in concurrent germ cell tumor and acute megakaryoblastic leukemia

TP53 and PTEN mutations were shared in concurrent germ cell tumor and acute megakaryoblastic leukemia

Abstract Background The occurrence of a mediastinal germ cell tumor (GCT) and hematological malignancy in the same patient is very rare. Due to its rarity, there have been only two reports of the concurrent cases undergoing detailed genetic analysis with whole-exome sequencing (WES), and the possibl...

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Bibliographic Details
Main Authors: Keiichi Akizuki, Masaaki Sekine, Yasunori Kogure, Takuro Kameda, Kotaro Shide, Junji Koya, Ayako Kamiunten, Yoko Kubuki, Yuki Tahira, Tomonori Hidaka, Takumi Kiwaki, Hiroyuki Tanaka, Yuichiro Sato, Hiroaki Kataoka, Keisuke Kataoka, Kazuya Shimoda
Format: Article
Language:English
Published: BMC 2020-01-01
Series:BMC Cancer
Subjects:
Acute myeloid leukemia
Germ cell tumor
TP53
PTEN
Online Access:https://doi.org/10.1186/s12885-019-6497-0

Internet

https://doi.org/10.1186/s12885-019-6497-0

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