MARCKS protein is phosphorylated and regulates calcium mobilization during human acrosomal exocytosis.

Acrosomal exocytosis is a calcium-regulated exocytosis that can be triggered by PKC activators. The involvement of PKC in acrosomal exocytosis has not been fully elucidated, and it is unknown if MARCKS, the major substrate for PKC, participates in this exocytosis. Here, we report that MARCKS is expr...

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Bibliographic Details
Main Authors: Marcelo J Rodriguez Peña, Jimena V Castillo Bennett, Osvaldo M Soler, Luis S Mayorga, Marcela A Michaut
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3660367?pdf=render