A New Method of the Visualization of the Double-Stranded Mitochondrial and Nuclear DNA.

The study describes the method of a sensitive detection of double-stranded DNA molecules in situ. It is based on the oxidative attack on the deoxyribose moiety by copper(I) in the presence of oxygen. We have shown previously that the oxidative attack leads to the formation of frequent gaps in DNA. H...

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Bibliographic Details
Main Authors: Anna Ligasová, Dmytro Strunin, Karel Koberna
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3688954?pdf=render