Oriented scanning is the leading mechanism underlying 5' splice site selection in mammals.

Splice site selection is a key element of pre-mRNA splicing. Although it is known to involve specific recognition of short consensus sequences by the splicing machinery, the mechanisms by which 5' splice sites are accurately identified remain controversial and incompletely resolved. The human F...

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Bibliographic Details
Main Authors: Keren Borensztajn, Marie-Laure Sobrier, Philippe Duquesnoy, Anne-Marie Fischer, Jacqueline Tapon-Bretaudière, Serge Amselem
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2006-09-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC1557585?pdf=render