Epigenomic annotation of noncoding mutations identifies mutated pathways in primary liver cancer.

Evidence that noncoding mutation can result in cancer driver events is mounting. However, it is more difficult to assign molecular biological consequences to noncoding mutations than to coding mutations, and a typical cancer genome contains many more noncoding mutations than protein-coding mutations...

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Bibliographic Details
Main Authors: Rebecca F Lowdon, Ting Wang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5363827?pdf=render