IGF2BP3 Modulates the Interaction of Invasion-Associated Transcripts with RISC

Insulin-like growth factor 2 mRNA binding protein 3 (IGF2BP3) expression correlates with malignancy, but its role(s) in pathogenesis remains enigmatic. We interrogated the IGF2BP3-RNA interaction network in pancreatic ductal adenocarcinoma (PDAC) cells. Using a combination of genome-wide approaches,...

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Bibliographic Details
Main Authors: Hanane Ennajdaoui, Jonathan M. Howard, Timothy Sterne-Weiler, Fereshteh Jahanbani, Doyle J. Coyne, Philip J. Uren, Marija Dargyte, Sol Katzman, Jolene M. Draper, Andrew Wallace, Oscar Cazarez, Suzanne C. Burns, Mei Qiao, Lindsay Hinck, Andrew D. Smith, Masoud M. Toloue, Benjamin J. Blencowe, Luiz O.F. Penalva, Jeremy R. Sanford
Format: Article
Language:English
Published: Elsevier 2016-05-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124716305289