Antifungal chemical compounds identified using a C. elegans pathogenicity assay.

There is an urgent need for the development of new antifungal agents. A facile in vivo model that evaluates libraries of chemical compounds could solve some of the main obstacles in current antifungal discovery. We show that Candida albicans, as well as other Candida species, are ingested by Caenorh...

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Bibliographic Details
Main Authors: Julia Breger, Beth Burgwyn Fuchs, George Aperis, Terence I Moy, Frederick M Ausubel, Eleftherios Mylonakis
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2007-02-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC1790726?pdf=render