Visceral adipose tissue imparts peripheral macrophage influx into the hypothalamus

Visceral adipose tissue imparts peripheral macrophage influx into the hypothalamus

Abstract Background Obesity is characterized by a systemic inflammation and hypothalamic neuroinflammation. Systemic inflammation is caused by macrophages that infiltrate obese adipose tissues. We previously demonstrated that high-fat diet (HFD)-fed male mice exhibited peripheral macrophage infiltra...

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Bibliographic Details
Main Authors: Kuan-Hui Ethan Chen, Nancy M. Lainez, Meera G. Nair, Djurdjica Coss
Format: Article
Language:English
Published: BMC 2021-06-01
Series:Journal of Neuroinflammation
Subjects:
Neuroinflammation
Hypothalamus
Fat transplant
Obesity
Macrophage
Sex differences
Online Access:https://doi.org/10.1186/s12974-021-02183-2

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