Visceral adipose tissue imparts peripheral macrophage influx into the hypothalamus
Abstract Background Obesity is characterized by a systemic inflammation and hypothalamic neuroinflammation. Systemic inflammation is caused by macrophages that infiltrate obese adipose tissues. We previously demonstrated that high-fat diet (HFD)-fed male mice exhibited peripheral macrophage infiltra...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2021-06-01
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Series: | Journal of Neuroinflammation |
Subjects: | |
Online Access: | https://doi.org/10.1186/s12974-021-02183-2 |