Gadd45b Acts as Neuroprotective Effector in Global Ischemia-Induced Neuronal Death

Gadd45b Acts as Neuroprotective Effector in Global Ischemia-Induced Neuronal Death

Purpose Transient global ischemia arising in human due to cardiac arrest causes selective, delayed neuronal death in hippocampal CA1 and cognitive impairment. Growth arrest and DNA-damage-inducible protein 45 beta (Gadd45b) is a wellknown molecule in both DNA damage-related pathogenesis and therapie...

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Bibliographic Details
Main Authors: Chang Hoon Cho, Hyae-Ran Byun, Teresa Jover-Mengual, Fabrizio Pontarelli, Christopher Dejesus, Ah-Rhang Cho, R. Suzanne Zukin, Jee-Yeon Hwang
Format: Article
Language:English
Published: Korean Continence Society 2019-02-01
Series:International Neurourology Journal
Subjects:
Global ischemia
Gadd45b
Mitochondrial dysfunction
Brain-derived neurotrophic factor
Neuroprotection
Online Access:http://www.einj.org/upload/pdf/inj-1938040-020.pdf

Internet

http://www.einj.org/upload/pdf/inj-1938040-020.pdf

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