Co-stimulation of the fc receptor and interleukin-12 receptor on human natural killer cells leads to increased expression of cd25

Co-stimulation of the fc receptor and interleukin-12 receptor on human natural killer cells leads to increased expression of cd25

Natural killer (NK) cells serve a critical role in the immune response against microbes and developing tumors. We have demonstrated that NK cells produce stimulatory cytokines (e.g., IFN-γ) in response to potent stimulation via immobilized IgG (to engage Fc receptors) and interleukin (IL)-12. CD25 i...

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Bibliographic Details
Main Authors: Megan C. Duggan, Amanda R. Campbell, Elizabeth L. McMichael, Kallan S. Opheim, Kala M. Levine, Neela Bhave, Michelle C. Culbertson, Tiffany Noel, Lianbo Yu, WE Carson
Format: Article
Language:English
Published: Taylor & Francis Group 2018-02-01
Series:OncoImmunology
Subjects:
natural killer cells
cd25
interleukin 2
interleukin 12
Online Access:http://dx.doi.org/10.1080/2162402X.2017.1381813

Internet

http://dx.doi.org/10.1080/2162402X.2017.1381813

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