Dihydropyrimidinase Like 2 Promotes Bladder Cancer Progression via Pyruvate Kinase M2-Induced Aerobic Glycolysis and Epithelial–Mesenchymal Transition

Dihydropyrimidinase Like 2 Promotes Bladder Cancer Progression via Pyruvate Kinase M2-Induced Aerobic Glycolysis and Epithelial–Mesenchymal Transition

BackgroundAerobic glycolysis and epidermal–mesenchymal transition (EMT) play key roles in the development of bladder cancer. This study aimed to investigate the function and the underlying mechanism of dihydropyrimidinase like 2 (DPYSL2) in bladder cancer progression.MethodsThe expression pattern of...

Full description

Bibliographic Details
Main Authors: Jun Zou, Ruiyan Huang, Yanfei Chen, Xiaoping Huang, Huajun Li, Peng Liang, Shan Chen
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-07-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
epithelial–mesenchymal transition
M2-type pyruvate kinase
dihydropyrimidinase like 2
bladder cancer
aerobic glycolysis
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2021.641432/full

Internet

https://www.frontiersin.org/articles/10.3389/fcell.2021.641432/full

Similar Items