Enriched Environment Cues Suggest a New Strategy to Counteract Glioma: Engineered rAAV2-IL-15 Microglia Modulate the Tumor Microenvironment

Enriched Environment Cues Suggest a New Strategy to Counteract Glioma: Engineered rAAV2-IL-15 Microglia Modulate the Tumor Microenvironment

Several types of cancer grow differently depending on the environmental stimuli they receive. In glioma, exposure to an enriched environment (EE) increases the overall survival rate of tumor-bearing mice, acting on the cells that participate to define the tumor microenvironment. In particular, envir...

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Bibliographic Details
Main Authors: Alessandro Mormino, Giovanni Bernardini, Germana Cocozza, Nicoletta Corbi, Claudio Passananti, Angela Santoni, Cristina Limatola, Stefano Garofalo
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-09-01
Series:Frontiers in Immunology
Subjects:
glioma
enriched environment
microglia/macrophages
NK cell
IL-15
adeno-associated virus
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.730128/full

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https://www.frontiersin.org/articles/10.3389/fimmu.2021.730128/full

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