Preliminary nanopore cheminformatics analysis of aptamer-target binding strength

<p>Abstract</p> <p>Background</p> <p>Aptamers are nucleic acids selected for their ability to bind to molecules of interest and may provide the basis for a whole new class of medicines. If the aptamer is simply a dsDNA molecule with a ssDNA overhang (a "sticky"...

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Bibliographic Details
Main Authors: Amin Iftekhar, Thomson Karen, Morales Eric, Winters-Hilt Stephen
Format: Article
Language:English
Published: BMC 2007-11-01
Series:BMC Bioinformatics