Quercetin based derivatives as sirtuin inhibitors

Polyphenols synthesized by plants and fungi have various pharmacological effects. The ability of polyphenols to modulate sirtuins has gained considerable interest due to the role of sirtuins in aging, insulin sensitivity, lipid metabolism, inflammation, and cancer. In particular, sirtuin 6 (SIRT6) h...

Full description

Bibliographic Details
Main Authors: Vladimír Heger, Jonna Tyni, Attila Hunyadi, Lubica Horáková, Maija Lahtela-Kakkonen, Minna Rahnasto-Rilla
Format: Article
Language:English
Published: Elsevier 2019-03-01
Series:Biomedicine & Pharmacotherapy
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332218374146