Spliceozymes: ribozymes that remove introns from pre-mRNAs in trans.

Group I introns are pre-mRNA introns that do not require the spliceosome for their removal. Instead, they fold into complex three-dimensional structures and catalyze two transesterification reactions, thereby excising themselves and joining the flanking exons. These catalytic RNAs (ribozymes) have b...

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Bibliographic Details
Main Authors: Zhaleh N Amini, Karen E Olson, Ulrich F Müller
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4094466?pdf=render